If you have dandruff one of the best things you can do is start using a shampoo that contains ketoconazole. Most people have heard of Head and Shoulders, which uses zinc to control dandruff, but actually ketoconazole shampoos are more effective at treating scalp conditions. Furthermore, ketoconazole (the active ingredient) is a mild ‘5-alpha-reductase inhibitor’, which may help reduce DHT in your scalp, which in turn may help reduce hair loss in men experiencing male pattern baldness.

Ketoconazole is a toxic chemical at sufficient volumes, but at the small volumes contained in these shampoos it effectively kills the common fungi that cause dandruff.

  • Lipogaine anti hair loss ketoconazole shampoo

    Lipogaine Big 3 Premium Hair Loss Prevention shampoo for Men and Women

    Around $25 for 8oz

    • Contains ketoconazole, which kills the fungi that causes dandruff and other scalp conditions and is thought to promote hair growth by inhibiting DHT
    • Contains saw palmetto, which may reduce DHT in the scalp
    • Contains emu oil, which may help reduce DHT and has other properties that are beneficial for hair growth
    • Contains niacin, which may help increase blood circulation in the scalp
    • Contains biotin, which may aid in the production of cells in the scalp
    • Contains vitamin B5, which may protect the hair from damage


    Buy online (USA)

    Buy online (UK)

  • Nizoral Anti Dandruff Shampoo

    Nizoral Anti Dandruff Shampoo

    Around $11 for 3.5oz

    Nizoral is by far the most well-known ketoconazole shampoo, but this is probably down to marketing more so than the product itself. That said it will do the job.

    • Contains 2% ketoconazole — the highest available concentration and therefore probably the most effective for stopping dandruff

    Buy online (USA)

    Buy online (UK)

  • DS Laboratories Revita High Performance Hair Growth Stimulating Shampoo

    DS Laboratories Revita Hair Growth Stimulating Shampoo Around $21 for 180ml

    • Contains ketoconazole, which kills the fungi that causes dandruff and other scalp conditions and is thought to promote hair growth in some individuals
    • Contains copper peptides, which may improve absorption of ingredients
    • Contains apple polyphenol, which may improve circulation in the scalp
    • Contains MSM, amino acids and biotin
    • Contains emu oil, which contains nutrients and may help nutrient absorption
    • Contains cysteine, the main component of hair (in terms of amino acid composition)
    • Contains taurine, which together with cysteine is thought to promote hair growth
    • Contains caffeine and carnitine tartrate, which may increase cell energy in scalp, increasing hair growth
    • Contains anti-oxidants, which may help protect cells from free radicals


    Buy online (USA)

    Buy online (UK)

  • Perfect Hair Shampoo Review

    Perfect Hair Anti Hair Loss Shampoo Around $20 for 8oz

    On paper this is a really great shampoo. It contains loads of great ingredients for hair loss prevention (see below), including ketoconazole, which reduces dandruff and scalp conditions and is also a mild 5-alpha-reductase inhibitor. However I have noticed that this shampoo has had some really bad reviews on Amazon, so it’s worth checking those out. Click the blue button to view the Amazon reviews.

    • Contains ketoconazole, which kills the fungus that causes dandruff and other skin conditions and may reduce DHT
    • Contains saw palmetto, which blocks 5-alpha reductase, which may reduce DHT when applied topically
    • Contains emu oil, a mild anti-inflammatory, which may also reduce DHT
    • Contains salicylic acid, which helps keep the pres clear of sebum
    • Contains biotin and horsetail (a source of silica), which are thought to help nourish hair
    • Contains niacin, which may help increase blood circulation to the scalp
    • Contains zinc, which kills the fungus that causes dandruff and other skin conditions
    • Contains pygeum, evening primrose oil and borage oil — all of which help inhibit 5-alpha reductase, thus potentially reducing DHT levels.
    • Contains caffeine, which has been shown in studies to promote hair growth


    Buy online (USA)

  • Regenepure DR anti DHT ketoconazole shampoo

    RegenePure Doctor Recommended Anti Hair Loss Shampoo Around $28 for 16oz

    Regenpure DR is a really great anti hair loss shampoo. It’s not marketed as an anti-dandruff shampoo, but does contain ketoconazole. This is really a great shampoo for hair loss sufferers, who sometimes have scalp conditions as well as the common causes of hair loss. Regenpure also contains saw palmetto (which may help block DHT in the scalp), zinc (which may help clear up skin conditions), salicylic acid (which helps clear the pores of dirt and sebum), niacin (which may increase blood circulation in the scalp, plus other ingredients that benefit the hair.

    • Contains niacin, which may help increase blood circulation in the scalp
    • Contains ketoconazole, which kills common scalp fungi and may also reduce scalp DHT
    • Contains saw palmetto, which may reduce DHT in the scalp
    • Contains linolenic acid, which may inhibit DHT locally
    • Contains emu oil, which is an anti-inflammatory. DHT is thought to cause inflammation in the scalp, leading to hair loss
    • Contains jojoba oil, which may increase hair growth
    • Contains salicylic acid, which helps clear sebum and dead skin cells from the scalp
    • Contains zinc, which helps reduce fungal infections in the scalp


    Buy online (USA)

    Buy online (UK)

  • Boots Ketoconazolw Shampoo

    Boots Anti Dandruff Shampoo Around GBP 8.19 for 20mg

    This is a bog standard ketoconazole shampoo with no added extras. Only available in the UK.

    • Contains 2% ketoconazole


  • Ketozal Anti Dandruff Shampoo

    Ketozal Anti-Dandruff Shampoo

    • Contains 2% ketoconazole

    Around $9 for 2.1oz

    Ketozal is a lesser known brand of ketoconazole shampoo. Like Nizoral, it’s nothing special but will do the job just fine.

Which is the best?

I recommend the RegenePure shampoo for anyone who is suffering from hair loss. If you also have a flaky, inflamed, irritated or itchy scalp purchase the RegenePure anti hair loss shampoo with the RegenPure DR scalp treatment with ketoconazole.

The Perfect Hair Shampoo contains all the best possible ingredients for a hair loss shampoo. However, due to its bad reviews I can’t recommend it at this moment. If anyone has any good or bad stories about any of these shampoos please leave a comment.

What else can you do to clear up dandruff and improve scalp condition?

Braggs Organic Apple Cider Vinegar

One of the best natural remedies for dandruff is an apple cider vinegar rinse. This is very easy to do. Simply dilute apple cider vinegar in water in a 1:1 ratio. Then apply the diluted solution to your scalp. Leave for 15 minutes and rinse. Do this every day until the dandruff clears up.

If you use an apple cider vinegar rinse, make sure you use an apple cider vinegar that contain something called “the mother”. This is removed from some apple cider vinegars during the manufacturing process, but is an important ingredient for this rinse.

Have you had dandruff? What did you do to treat it?

Let us know in the comments.

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9 thoughts on “6 Shampoos that Contain Ketoconazole — which is the best?”

    1. I started using the Perfect Hair Shampoo and had great results. My hair thickened up and stopped breaking off . It seemed to become stronger. I will continue to use as long as it is available. I cannot understand how it could get a bad review, it is a great shampoo for stopping hair loss. I have several of my friends using it and they like it too. You do have to follow the directions and leave it on for a few minutes while massaging your scalp, but how hard it that? It only takes less then three or four minutes and that is a small price to pay to have thicker hair.

      M. S Wright

  1. Hi.

    I just want to point out, that Ketoconazole 1% or 2% Shampoos are also used for a skin fungal infection called “Tinea Versicolor”. Which is a monthly lifetime treatment, because It will come back every 2 years. Prescription wise, it dose the job, but doesn’t lather very well. Do any of these lather well?

  2. Hi

    I’m 25 and I am having dandruff problem for past 3 years. My hair becomes dry and frizzy after hair wash, after a day or two it becomes greasy as if I have applied oil ( I don’t apply oil ) I have hair fall problem too with receding hair in front. My hair is not very lengthy. I want to increase the volume of my hair and get rid off dandruff. Can u suggest shampoos and some home remedies for the same. I currently using head and shoulders anti dandruff shampoo.

  3. I had really stubborn dandruff and consulted a dermatologist. What they suggested works like a dream for me. It’s a rotation between three types of common shampoos. They said the fungus can adapt to the zinc levels, for example, if you only use one kind, which was what I’d been doing. Now, each time I wash my hair, I rotate between a ketoconazole (like Nizoral), a zinc (like head n shoulders) and a selenium sulfide (like Selsun Blue). works wonders! The dandruff never returns.

  4. Update: revita has only 0.25% keto* so basically the lowest amount possible for them to put it on the list ingredients, but not enough for it to be clinically effective.

    * source hgspecialist.com

  5. I had stubborn dandruff , it was so thick and scabby and my scalp would itch something awful. It looked ugly and ot was embarrassing to have. My Doctor prescribed me 2 percent ketoconazole shampoo..AWESOME!!! took it away completely within 2 weeks and you can buy 1 percent ketoconazole (nizoral) over the counter which im sure takes a little longer but will do the job. Hope this was helpful.

  6. Apply yoghurt to hair – plain, fat or non fat. Can use your fingers. Massage in. Leave till it dries before washing with any shampoo. I have very long & thick hair so half of it is already dried up by the time I finish applying. For short hair, May leave for half hr to one hour. INSTANT RESULT – in one application. I get lazy in the winter months and don’t use it coz your head does feel cold, since yoghurt is cold and so my dandruff comes back in winters. Tried heating it once in microwave but it coagulates. You could try leaving it out to reach room temp. I use it regularly before every wash through spring-summer-fall – not a single flake in my head at that time

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