Hair Restore MD Hair Loss DHT Blocker Shampoo Review + Ingredients Explained -

Hair Restore MD Hair Loss DHT Blocker Shampoo Review + Ingredients Explained

I was amazed at the sheer number of active ingredients in this shampoo. It’s taken me absolutely ages to go through them all and write up how each of these ingredients benefits hair growth.

Full ingredients list

  • Aloe Barbadensis (Aloe Vera) Leaf Juice*
  • Urtica Dioica (Nettle) Extract*
  • Camellia Sinensis (Green Tea) Leaf Extract*
  • Chamomilla Recutita (Matricaria) Flower Extract*
  • Sage Extract*
  • Equisetum Arvense Extract*
  • Panax Ginseng Root Extract*
  • Saw Palmetto Fruit Extract*
  • Decyl Glucoside
  • Coco-Glucoside (natural cleansers)
  • Amla Fruit Extract*
  • Glycerin* (Vegetable)
    • Arginine
    • Lactic Acid
    • Glycine Soja (Soybean) Germ Extract
    • Triticum Vulgare (Wheat) Germ Extract
    • Scutellaria Baicalensis Root Extract)
  • Biotin (Vitamin B7)
  • Caffeine
  • Niacinamide (Vitamin B3)
  • Calendula Flower Extract*
  • Grape Seed Extract*
  • CAPALGIN® (Chondrus Crispus Extract)
  • Clover Flower Extract
  • DEFENSCALPTM (Epilobium Angustifolium Flower/Leaf/Stem Extract)
  • Gotu Kola Extract*
  • Panthenol (Provitamin B5)
  • Apple Fruit Extract
  • Apple Fruit Cell Extract
  • Argan Sprout Stem Cell Extract
  • Biotinoyl Tripeptide-1
  • Grape Fruit Cell Extract
  • Soy Isoflavones
  • Pumpkin Seed Oil*
  • Argania Spinosa (Argan) Kernel Oil*
  • Tocopherol (Vitamin E)
  • Beta-Carotene (Provitamin A)
  • Cymbopogon Schoenanthus (Lemongrass) Oil*
  • Salvia Officinalis (Sage) Oil*
  • Vetiveria Zizanioides (Vetiver) Oil*
  • Lavandula Angustifolia (Lavender) Oil*
  • Pinus Palustris (Pine) Needle Oil*
  • Atlas Cedar Oil*
  • Glycol Distearate (Vegetable)
  • Beta-Sitosterol
  • Ω6 CERAMIDE® (Safflower Oil/Palm Oil Aminopropanediol Esters)
  • Silk Amino Acids
  • Arginine
  • Guar Gum
  • Gluconolactone
  • Sodium Benzoate (natural preservative)
  • Citric Acid

*Organic Ingredients

For a hair loss shampoo this is a lot cheaper than some of the other ones I’ve reviewed. Despite the budget label and packaging the ingredients look very good. In fact, there are so many good ingredients in this shampoo it’s quite remarkable. This is certainly one of the best hair loss shampoos I’ve ever seen.

Ingredients explained

Hair Restore MD hair loss DHT blocker

Nettle, saw palmetto, caffeine, beta sitosterol, Amla fruit extract and soy isoflavones: may reduce DHT

These natural plant extracts are widely thought to reduce the production of DHT, which is the hormone that causes male pattern baldness.

Camellia Sinensis (Green Tea) Leaf Extract*

Green tea contains the polyphenols EGCG, which is a “direct antagonist of androgen action”. That means it may help reduce the effect of DHT on the hair follicles. DHT is the androgen hormone that causes male pattern hair loss. However, it’s uncertain as to whether these polyphenols would have a significant effect when used in a shampoo (by comparison to a leave in topical).

Chamomilla Recutita (Matricaria) Flower Extract*

According to a study in Tehran, Matricaria was shown to increase hair growth when used in conjunction with minoxidil. The researchers believe this is because the plant extract reduces DHT by inhibiting the 5-alpha-reuctase enzyme. Again, the same results may not necessarily translate when used in a shampoo, since the ingredients are washed away from the scalp, reducing absorption of the active chemicals.

Equisetum Arvense Extract*

Panax Ginseng Root Extract, Arginine, Safflower and Niacinamide

Studies have shown that these ingredients improve blood circulation in the scalp by increasing the growth factor VEGF, which is needed for the formation of the blood vessels that supply blood to the hair.

Amla Fruit Extract*

I’ve seen only one study claiming amla is a 5 alpha reductase (5ar) inhibitor. There are no other studies confirming this that I can see. According to that study, amla effectively reduces DHT via the action of inhibiting 5ar.

Glycine Soja (Soybean) Germ Extract

Scutellaria Baicalensis Root Extract: Upregulates Wnt signalling pathways

I’ve seen one study, which examined this plant extract’s effect on hair follicle growth and the researchers concluded the chemical works by activating Wnt signalling pathways in the hair follicles. These signalling pathways (when activated) seem to ‘turn on’ hair growth.

Biotin (Vitamin B7)

Although biotin is included in absolutely loads of topical hair loss treatments, I’ve seen no empirical evidence that it increases hair growth.

Calendula Flower Extract*

Calendula has anti-inflammatory properties. I consider inflammation to be one of the most significant causes of hair loss. Numerous studies have shown that reducing scalp inflammation has a positive impact on hair growth.

Grape Seed Extract*

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CAPALGIN® (Chondrus Crispus Extract)

Capalgin is an interesting ingredient that I’ve not seen before. According to their own documentation it somehow maintains the expression of the ß1-integrin protein in the scalp. The ß1-integrin seems to play an important role in keeping hair in the growth (anagen) phase.

Clover Flower Extract

Clover may help reduce inflammation.

DEFENSCALP (Epilobium Angustifolium Flower/Leaf/Stem Extract)

According to their literature, Defenscalp inhibits the enzyme 5-alpha-reductase, which may reduce DHT. This is another hair loss treatment I’ve never heard of but will look into and write up as a future article. I’m amazed at the number of active ingredients in this shampoo!

Gotu Kola Extract*

According to this study Gotu Kola inhibits the STAT signilling pathway in the scalp. Apparently expression of the STAT pathway leads to reduced hair growth. This is an interesting approach to hair loss prevention that I’ll be writing up at a later date.

Apple Fruit Cell Extract

I have seen some research suggesting appl e stem cells may boost hair growth. However, the reearch I’ve seen was conducted on specific varieties of apples. That said, it’s likely there are similar properties found in most apples.

Biotinoyl Tripeptide-1

Although there are a lot of hair care ad skin care products that contain this ingredient, I’ve seen no research to suggest it increases hair growth.

Grape Fruit Cell Extract

This might be referring to stem cells or perhaps Proanthocyanidins. Several studies have shown that extracts from apple cells seem to increase hair growth. The exact action by which they do that is – as far as I know – unknown.

Lavandula Angustifolia (Lavender) Oil*

Lavender oil was shown in one study to increase the growth phase of hair and stimulate the development of hair mast cells.

Pinus Palustris (Pine) Needle Oil*

Lavender oil was shown in one study to increase hair growth by stimulatin gthe production of mast cells.


I’ve never seen so many active ingredients in a hair loss shampoo. This is a very good shampoo with a lot of great ingredients.