One fact which goes against this theory is that many men with high levels of circulating DHT don’t lose their hair
It’s long been proven that Dihydrotestosterone (DHT) – an androgen hormone – is the leading cause of male pattern hair loss. DHT is a highly potent compound formed when testosterone combines with 5-alpha-reductase. This enzyme is found in the prostate, gonads, as well as the skin. In males about 70% of circulating DHT is formed this way, using about 10% of the testosterone produced each day.
DHT binds to specific androgen receptors at the base of the hair follicles. Inside the nucleus of each hair cell, a process begins where the healthy hair follicle is gradually miniaturised — the classic precursor to hair loss. The natural healthy hair cycle is disturbed, with the growth (or anagen phase) reduced, and the shedding (or telogen) phase extended.
There are several DHT blockers available, both pharmaceutical and natural (more below). Logically, if you could prevent DHT attacking scalp hair follicles you would eradicate 95% of hair loss. One fact which goes against this theory is that many men with high levels of circulating DHT don’t lose their hair. And it cuts both ways. Men who do lose their hair may not have particularly high levels of DHT. This has led trichologists to surmise that the sensitivity of the scalp to DHT is more critical to baldness than DHT levels themselves. But what could cause this variation in scalp sensitivity?