…we discovered that proanthocyanidins extracted from grape seeds promote proliferation of hair follicle cells isolated from mice by about 230% relative to controls (100%); and that proanthocyanidins possess remarkable hair-cycle-converting activity from the telogen phase to the anagen phase
In the above study, proanthocyanidins were shown to increase the proliferation hair follicle cells. According to the research the proanthocyanidins were more effective then minoxidil and increasing cell proliferation in the follicles.
The morphology of the hair follicle cells on the rounded appearance characteristic of undifferentiated juvenile cells. This suggests that the mechanism of action for proanthocyanidins may involve the prevention of cell differentiation and the retention of the growing phase.
It’s not completely clear how proanthocyanidins increase hair growth but it seems they are at least to some extent effective. I shall investigate this further to try to determine exactly how the chemicals are triggering hair growth.