There are hundreds of topical hair loss products on the market. But of all those hundreds that I’ve reviewed these are the only ones I would recommend.

A good topical hair regrowth product is a good weapon in your arsenal in the battle to regrow your hair. I get a lot of questions from readers who want to know what really are the best topical hair loss treatments available in the world. So I spent a lot of time researching the ingredients of the topicals I could find, then I narrowed down the list to only the very best.

I’ve collected all the ingredients together on this page and put it all into one convenient list, so you can see my conclusions and make up your own mind.

  • DS Labs Spectral DNC N

    DS Labs Spectral DNC N

    Around $25 for 2oz

    • Gingseng extract may promote blood circulation in the scalp
    • “Nanoxidil” (a new form of Minoxidil, developed by DS Labs) increases blood circulation in the scalp and is thought to penetrate the scalp skin better than normal Minoxidil
    • Amenixel is thought to improve blood circulation in the scalp and may help reduce perifollicular fibrosis
    • Arginine may help improve blood circulation in the scalp
    • Uses nanosomes to improve delivery of ingredients
    • Contains copper peptides, which may help reduce inflammation
    • Contains Adenosine, which has been shown to be effective in reducing hair loss in several major hair loss studies
    • Contains polyphenols, which are thought to help improve blood circulation in the scalp and according to DS Labs help regrowth along the hair line
    • Citrulline is a precursor to arginine, which helps improve blood circulation
    • Contains natural plant stem cells, which may help increase cell growth in the scalp
    • Contains Biotin, which supports healthy hair
    • Retinol is an antioxidant, which is thought by some to reduce hair loss

    Ingredients

    Buy online (USA)

    Buy online (UK)

  • Wick and Strom Apex Crown Topical hair loss solution

    Wick & Strom Apex Crown

    Around $20 for 4oz

    This is the only topical I’ve seen that contains ketoconazole, which makes it stand out. It contains a huge array of proven effective ingredients. And it’s super cheap! Amazon are also selling it at 15% off when you buy three bottles. This is a world class topical.

    Ingredients

    Buy online (USA)

  • Follinox 5

    Follinox 5

    Around $100 for 1oz

    • Emu oil is a good natural carrier oil with anti DHT, anti inflammatory and bactosteriatic properties
    • Contains 2% Minoxidil, which increases blood circulation in the scalp
    • Contains a vitamin complex, which may be high in antioxidants (which scavenge free-radicals) and may also help improve absorption of other ingredients
    • Retinol is an antioxidant, which is thought by some to reduce hair loss
    • Capsicum extract may help increase blood circulation in the scalp
    • Linoleic/alpha linonianic acid
    • Nettle and pygeum are natural DHT blockers
    • He shu wu is known in China for its hair growth promoting properties
    • Biotin is thought to help with hair health but it is not known if this works when applied topically
    • Zinc is known to help kill the common scalp fungi that causes dandruff and may also reduce hair loss
    • Kelp contains iodine, which is helpful in regulating healthy thyroid function (over active thyroid is a cause of hair loss) — however it is unlikely that this will have any benefit when used topically
    • Folic acid helps the body produce keratin
    • Arginine may help increase blood circulation in the scalp
    • Borage oil is rich in GLA, which may inhibit DHT

    Ingredients

    Buy online (USA)

  • Revivigon topical hair loss spray

    Revivogen

    Around $100 for 1oz

    • Contains linoleic and oleic acid, which prevent the conversion of testosterone into DHT
    • Contains saw palmetto, which may also prevent DHT production in the scalp
    • Studies suggest Beta Sitosterol also prevents conversion of testosterone to DHT by inhibiting the enzyme 5-alpha reductase
    • Caffeine may stimulate hair growth, though this is not proven
    • Procyanidin B2 (from apple polyphenols) is believed to stimulate blood circulation in the scalp
    • Zinc fights against common scalp fungi, helping to promote a healthy scalp environment

    Ingredients

    Buy online (USA)

    Buy online (UK)

  • Lipogaine topical hair loss treatment

    Lipogaine

    Around $25 for 2oz

    • Contains 5% Minoxidil, which is clinically proven to increase blood circulation in the scalp and reduce hair loss in some individuals
    • Contains azelaic acid, which is also thought to promote blood circulation on the scalp
    • Contains retinol (vitamin A), an antioxidant which is thought to help reduce hair loss
    • Contains saw palmetto, which reduces the production of DHT (the most significant cause of hair loss in men)

    Ingredients

    Buy online (USA)

    Buy online (UK)

  • Pura D Or topical hair loss serum

    Pura D’Or Topical Hair Loss Serum

    Around $22 for 4oz

    Ingredients

    Buy online (USA)

  • DS Labs Spectral RS

    DS Labs Spectral RS

    Around $30 for 2oz

    • Contains nanosomes, which improve the absorption of the ingredients
    • Capsicum may help improve blood circulation in the scalp
    • Procyanidins may help improve blood circulation in the scalp
    • Adenosine may increase the hair’s growth phase, thus reducing hair loss
    • Amenixel may help improve blood circulation in the scalp
    • Retinol is an antioxidant and is thought to promote hair growth in some cases
    • Copper peptides benefit hair growth by reducing inflammation and possibly increasing blood circulation.

    Ingredients

    Buy online (USA)

    Buy online (UK)

  • Crinagen Scalp Therapy Hair Loss Topical

    Crinagen

    Around $25 for 2oz

    • Azelaic acid is thought to increase blood circulation in the scalp
    • Zinc is known to reduce dandruff and in some case has been shown to reduce hair loss
    • Niacin may increase blood circulation in the scalp

    Ingredients

    Buy online (USA)

    Buy online (UK)

  • GowEasy Minoxidil and DHT Inhibitor

    GowEasy Minoxidil and DHT Inhibitor

    Around $27 for 2oz

    • Contains linoleic and oleic acid, which prevent the conversion of testosterone into DHT
    • Contains 5% minoxidil (highest commercially available strength) to increase blood flow to the hair
    • Contains 15% azelaic acid, which may reduce DHT in the scalp
    • Caffeine may stimulate hair growth, though this is not proven

    Ingredients

    Buy online (USA)

  • JustNatural Grow New Hair Topical Hair Growth Treatment

    Just Natural Organic Hair Growth Spray

    Around $45 for 4oz

    • Pumpkin seed and flaxseed contain GLAs that prevent production of DHT
    • Saw palmetto, nettle and pygeum are three of the most well known natural DHT blockers
    • Green tea is a source of antioxidants and may help reduce DHT production
    • Grapeseed and ginkgo biloba may help improve blood circulation
    • High in nutritious organic ingredients and no “artificial” chemicals

    Ingredients

    Buy online (USA)

  • Murad Hair Loss Serum

    Murad Hair Growth and Scalp Serum

    Around $27 for 1.7oz

    • Contains salicylic acid, which helps break down sebum, built-up cosmetics and pollutants in the scalp, helping to improve scalp health
    • Contain Biotin, which may benefit hair and scalp health — see What Role Does Biotin Play in Hair Growth?
    • Contains capsicum frutescens fruit extract (chilli pepper), which may help bring blood to the hair follicles
    • Contains pomegranate and other fruits that are high in antioxidants

    Ingredients

    Buy online (USA)

  • Revellus human stem cell hair growth serum

    Revellus Human Stem Cell Hair Growth Serum

    Around $99 for 1.6oz

    This is an interesting product. It contains proteins derived from human stem cells! I posted an article on stem cells for hair growth a while back and it looks as though there’s a lot of potential. However, we don’t know for sure how the company has extracted the proteins and what exactly they are. Update coming soon!

    • Uses stem cells to promote hair growth. Could be beneficial but there is very little evidence to confirm the stem cell extracts in this product will increase hair growth.
    • Aloe vera is a natural plant extract, which has shown a lot of promise in improving skin health and some research suggests it may benefit hair health
    • Bamboo is a source of silica, which is why you often see it in hair products. Silica helps repair connective tissue, which is key for hair growth and skin health
    • Contains grapefruit — a source of citrulline (a precursor to arginine), which may help improve blood circulation by increasing NO2
    • Contains saw palmetto, which studies show helps reduce DHT, the primary cause of adrogenic alopecia
    • Contains “hydrolized keratin”. This is interesting but also lacks evidence to suggest it may benefit hair growth. Hair is made of keratin but we have no evidence to suggest that applying keratin to the scalp will increase hair growth, since keratin is made in the follicle base via a process of keratinization, where amino acids are turned into keratin. Whether adding keratin to the scalp would increase hair growth is debatable — I would say it’s unlikely but interesting nonetheless.

    Ingredients

    Buy online (USA)

What to look for in a topical hair loss treatment

These treatments are applied directly to the scalp, where they perform three key functions:

  • Increase blood flow to the hair — using ingredients like minoxidil, niacin, arginine and polyphenols
  • Reduce DHT in the scalp — using ingredients like linoleic and oleic acid, saw palmetto, ketoconazol and azelaic acid
  • Support healthy scalp skin — using ingredients like biotin, antioxidants and other vitamins and minerals

What is the optimal strategy for using a topical hair loss treatment?

If you’re going to spend the money on these treatments you might as well get the maximum benefit from them. For me there are three categories of topical treatments: circulation boosters, DHT blockers and nutrient-rich topicals. In an ideal world you want to get the benefit of all three. You’re recommended to use minoxidil treatments (like Spectral DNC) no more than twice a day, so you want to use a minoxidil treatment before bed and after you shower in the morning. In between (for example when you get back from work) try using a DHT blocker topical (like Revivogen) or a natural nutrient rich topical like JustNatural. Before using a topical, vigorously brush your scalp with a hard bristled boar brush to exfoliate and increase blood flow to the hair roots.

Which is the best topical you can buy?

Best Topical Hair Loss Treatments

These are all very good products with s lot of distinct benefits, but for me there is one clear winner — Spectral DNC N. The technology in this topical is really clever and objective orientated. It contains what is probably the most effective form of minoxidil (in the form of the smaller Nanoxidil), copper peptides and even stem cells. You might find that if monixidil has never worked for you, this might be worth trying. However, if you find DNC N doesn’t work for you (in which case its likely that no minoxidil based product will work for you), your next best bet might be Follinox 5, which contains loads of beneficial ingredients your scalp needs to grow hair. Failing that Spectral RS might be your next best bet, which is a complete alternative to minxodil.

Have you tried any of these products? Let us know if they worked for you.

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