In order to investigate and evaluate the effects of red deer antlers on hair growth in the full-thickness wound healing model, Sprague-Dawley rats were given incision wounds through the full thickness of their dorsal skin and deer antler was applied for 40 days. At specified intervals thereafter (4, 8, 16, 32 and 40 days), the animals were sacrificed and the wound site skins were excised, processed, and sectioned. At post-injury days 16, 32 and 40, longer and more active new hair appeared around the healing wound of antler-treated skin. Histological studies showed that the antler extract markedly increases the depth, size, and number of hair follicles. Expression of IGF-I (insulin-like growth factor) mRNA was detected by RT-PCR and real time RT-PCR. The result showed that the expression of IGF-I (days 16, 32, and 40) was obviously up-regulated in antler-treated skins compared to control skins. Similar results were seen in the ELISA analysis to quantify the IGF-I expression. These results support the notion that wound healing can cause hair growth by enhancing the expression of IGF-I. Deer antler extract appears to have the potential to promote hair growth and could be used in hair growth products.
Via PubMed
Velvet deer antler, a powder derived from the antlers of deer during their regenerative growth phase, has been used in traditional medicine for centuries. It is rich in growth factors, including insulin-like growth factor-1 (IGF-1), which has led to its use as a health supplement for improving recovery, athletic performance, and overall vitality. Recently, velvet deer antler has gained attention for its potential in promoting hair growth when applied topically. But what does the science say about this?
In this article, we’ll explore real studies that have examined the effects of topical velvet deer antler on hair growth, explain how it works, and assess its potential as a hair growth treatment.
How Velvet Deer Antler Works for Hair Growth
The primary mechanism behind velvet deer antler’s potential for hair growth lies in its high concentration of growth factors—particularly IGF-1 and transforming growth factor-beta (TGF-β). These growth factors are naturally present in velvet deer antler and are essential in regulating cell growth, tissue regeneration, and wound healing. They have been studied for their ability to enhance hair follicle activity and stimulate the hair growth cycle.
Key Mechanisms Include:
Increased IGF-1 Levels: IGF-1 plays a key role in promoting the anagen (growth) phase of the hair cycle. Higher levels of IGF-1 in the scalp are associated with increased hair follicle activity and hair regeneration.
Improved Blood Circulation: Velvet deer antler has vasodilatory effects, improving blood flow to the scalp, which enhances the delivery of nutrients and oxygen to hair follicles.
Reduction of Inflammation: Chronic inflammation can impair hair growth. Velvet deer antler contains anti-inflammatory compounds that may help reduce inflammation in the scalp, creating a more favorable environment for hair follicles.
Studies on Velvet Deer Antler and Hair Growth
While research specifically focusing on velvet deer antler as a hair growth agent is limited, some studies have explored the broader effects of IGF-1, growth factors, and topical application of regenerative compounds on hair growth. Here, we summarize the most relevant studies:
Study 1: IGF-1 and Hair Growth
A study published in The Journal of Investigative Dermatology in 2003 examined the role of IGF-1 in hair follicle health. Researchers found that IGF-1 was a critical factor in promoting the transition of hair follicles from the resting (telogen) phase to the active growth (anagen) phase.
Study Results: The study showed that higher levels of IGF-1 were associated with a significant increase in hair follicle activity, leading to accelerated hair growth. IGF-1 was found to improve the proliferation of keratinocytes, the cells responsible for producing hair.
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Whats the best shampoo for hair loss? “Increased levels of IGF-1 in the scalp correlated with enhanced hair follicle activity and a faster transition to the anagen phase, suggesting its key role in hair regeneration.” ~ [Source: The Journal of Investigative Dermatology, 2003]
Although this study did not involve velvet deer antler directly, it highlights the importance of IGF-1 in hair growth, which is a key component of velvet deer antler extract.
Study 2: Topical Growth Factors for Hair Regrowth
A more specific study, published in Clinical, Cosmetic and Investigational Dermatology in 2014, looked at the effects of a topical solution containing growth factors (including IGF-1) on hair regrowth in individuals with androgenetic alopecia (pattern hair loss).
Study Results: The topical solution containing growth factors, including IGF-1, significantly improved hair density and thickness in participants after 12 weeks of application. The researchers noted that growth factors promoted the proliferation of dermal papilla cells, which are essential for hair follicle development.
“Participants using a growth factor-rich topical solution showed an increase of 18.3% in hair density after 12 weeks, demonstrating the potential of growth factors in treating hair thinning.” ~ [Source: Clinical, Cosmetic and Investigational Dermatology, 2014]
This study is highly relevant to velvet deer antler, as the growth factors found in velvet antler, including IGF-1, are similar to those used in the study.
Study 3: Anti-Inflammatory Effects and Hair Follicle Protection
A 2008 study published in Experimental Dermatology explored how inflammation impairs hair follicle function and how reducing inflammation can improve hair growth. The researchers found that chronic inflammation around hair follicles can lead to miniaturization, a hallmark of androgenetic alopecia.
Study Results: The study demonstrated that reducing inflammation in the scalp could restore hair follicle function and improve hair density.
“Reducing scalp inflammation improved hair follicle function, leading to a significant increase in hair growth and density in affected areas.” ~ [Source: Experimental Dermatology, 2008]
Given velvet deer antler’s anti-inflammatory properties, it’s reasonable to suggest that its application could help reduce scalp inflammation and protect hair follicles from damage.
How to Use Velvet Deer Antler for Hair Growth
Velvet deer antler is available in various forms, including supplements and topical solutions. For hair growth, topical application is believed to be the most effective route, as it allows the growth factors to directly interact with the scalp and hair follicles.
Topical Application:
Velvet Antler Serums: These serums are designed for scalp application and are often combined with other hair growth-promoting ingredients like caffeine or biotin. Apply a few drops to the scalp daily, focusing on areas of thinning or hair loss.
Massage: Gently massage the serum into the scalp for a few minutes to improve absorption and increase blood flow to the follicles.
Oral Supplements:
While topical application is preferred for hair growth, velvet deer antler is also available as an oral supplement. Taking velvet antler orally may help increase systemic levels of growth factors, potentially supporting hair growth from within. The typical dosage ranges from 500 mg to 1,000 mg per day, but it is always advisable to consult with a healthcare professional before starting any supplement regimen.
Conclusion
Velvet deer antler, rich in growth factors such as IGF-1, holds potential for promoting hair growth through its ability to stimulate hair follicle activity, improve scalp circulation, and reduce inflammation. Although direct studies on topical velvet antler for hair growth are limited, the research on growth factors and their role in hair regeneration is promising.
Topical application of velvet deer antler, in combination with other hair growth-promoting strategies, may offer a supportive treatment for individuals experiencing hair thinning or pattern hair loss. As more studies emerge, velvet deer antler could become a recognized tool in the fight against hair loss, particularly for those looking for natural and regenerative options. Always consult with a healthcare professional before starting any new treatment.
